NU to upgrade machine and electronics shops

For more information on NU’s plan to upgrade shop support, see this article: https://www.facilities.research.northwestern.edu/news/machine-and-electronic-shops-get-retooled-construction-begins .  IMSERC will be managing the new electronics shop and is currently looking to hire a new electronics engineer.

Applications for Bioanalytical

IMSERC has a large pool of modern instrumentation for bioanalytical scientists. Our center is integrated with the Chemistry Department at Northwestern University where scientists run their experiments on a 24/7 basis. From monitoring reactions to full structure elucidation, researchers and students have access to a variate of techniques that can be used for:

Crystallographic atomic structure determination, identification, and refinement of small bio-organic and bio-inorganic compounds for extraction of structural information such as:

  • Determination of unit cell and bonding environment (bond-lengths, bond-angles, cation-anion coordination, site-ordering, etc.)
  • Determination of packing of molecules
  • Determination of Hydrogen bonding
  • Determination of enantiomers
  • Refinement of modulated and twinned structures (incommensurate, commensurate, composite superstructures)
  • High resolution data for charge density measurement and precise assignment of atoms with similar chemical environment
  • Evaluation of sample purity (sensitivity of ~2% by weight)
  • Quantitative determination of individual crystalline phases and impurities in mixtures of powder
  • Monitor reactions in real time as a function of time, temperature, pressure, and gas flow/pressure
  • Investigate decomposition mechanism
  • In-situ monitoring of crystallization processes with increasing temperature

Thermal analysis which can be coupled with GC-MS for the determination of:

  • Melting point using either Differential Thermal Analysis or Differential Scanning Calorimetry
  • Crystallization transition using either Differential Thermal Analysis or Differential Scanning Calorimetry
  • Glass transition using Differential Scanning Calorimetry
  • Decomposition temperature using ThermoGravimetric analysis which can be coupled with GC-MS for the identification of the decomposition products
  • Temperature of combustion with ThermoGravimetric analysis and identification of combustion volatiles using GC-MS

Qualitative and Quantitative elemental analyses

  • Accurate determination of concentration of Carbon, Hydrogen, Nitrogen, and Sulfur in solid materials by using combustion CHNS analysis
  • Halide determination (Chlorine, Bromide, Iodine) in solids or liquids using X-ray Fluorescence Spectroscopy
  • Survey of impurities and elements heavier than Sodium with X-ray Fluorescence Spectroscopy

Optical spectroscopy

  • Determination of functional groups and likely solvnet molecules using Infrared (IR) spectroscopy
  • Vibrational stretches using Raman and IR Spesctroscopy
  • Color, band gap, and absorption measurements using Ultra-violet (UV), visible (Vis), and IR spectroscopies
  • Photoluminescence, lifetime phosphorescence, and emission measurements using spectrofluorimeter
  • Optical rotations and quantification of enantiomers using polarimetry

NMR shutdowns in next a few weeks

The Ag500 won’t be available from 9am of 9/15 (Thursday) to 4pm of 9/16 (Friday) and 9am of 9/29 (Thursday) to 4pm of 10/3 (Monday) due to power shutdown in the building.

The HCN600 won’t be available from 9am of 9/2 (Friday) to 4pm of 9/6 (Tuesday) due to processed chilled water interruption in the building.

Please plan your experiments ahead.

IMSERC NMR

FTIR Errors- Resolution

Many users have reported an error during background dSave Peak Positionata collection: “Peak Location out of range, save peak position: -1422.  Measurement file not found”.  To resolve, click “Save Peak Position”, on the Check Signal tab.  The manual has been updated to do this every time when checking peak intensity.

IMSERC to Implement Firewall June 1st

In order to better secure your data, reduce the risk associated with malicious attacks on our instrument computers and make our network run more efficiently, IMSERC will be blocking all external traffic at our firewall.  This will not impact NUCORE or IMSERC’s website.  Also, if you have data delivered by email directly from instruments, that will continue as before.

However, if you access data directly through FTP from outside NU, this will no longer work.  In order to access data, you will need to log in to the NU VPN which requires an NU NetID.  If you are currently accessing data by FTP and do not have a netID, please let Andy Ott know and I will have a NetID created for you and work to make sure the login and data transfer works before we turn on the firewall.

Ask SIRI?!

Having trouble with instrumentation in your lab on the Evanston campus.  IMSERC’s “Small Instrumentation Repair and Installation” team can help.

IMSERC staff will provide 30 minute consultation on options to care for equipment and then bill time at normal staff hourly rates.  In many cases, we have been able to repair equipment for less than 10% of vendor quoted costs.

If you need assistance see http://imserc.facilities.northwestern.edu/opticaltrace/siri/ for details on types of service required or contact Andy Ott to obtain assistance.

Check your WildCard’s expiration date to avoid IMSERC lockout


wildcardCheck Your WildCard’s Expiration Date:

If you Wildcard expires, you will not be able to access IMSERC after hours.  Replace your card before it expires to avoid being locked out.  When you replace your WildCard, make sure to request a new INDALA card and then send the new INDALA card number to chemhelp@u.northwestern.edu and we will activate the new card for you.

New MNOVA Licenses Available

IMSERC has renewed our site license maintenance agreementMNovaUpgrade with MNova for the next three years.  In order to upgrade, map \\imsercdata.northwestern.edu\public, open MNova open Get/Install Licenses in the help menu.  The new licenses are at and public\MNova\License\Northwestern University Campus MNOVA.zip (just click on the zip file and all of the licenses unpack).

For those of you who had downgraded due to the bug loading MALDI files, the most recent version on MNova has resolved that problem.  MNova opens both Bruker and Agilent 2D spectra collected using NUS.  If you don’t know what that means, talk to Yongbo or Yuyang about how you can collect higher resolution 2D spectra in less than half the time you use today.