Heteronuclear NMR

With much larger chemical shift dispersion and less background signals, hetronuclear NMR provides attractive alternative over proton for drug discovery and material research. The figure below compares the proton and carbon spectra for same compound. You can clearly see every carbon peak is well resolved but the proton is severely overlapped.

IMSERC NMR has the capability to do heteronuclear NMR data collection for any nucleus ranging from 10 to 40% of proton frequency, including 19F. We have an unique HFX probe capable of running 2D 1H-19F correlation (HOESY) experiment.

NMR Protein Structure Elucidation Project Request

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